BackgroundThe COVID-19 pandemic has had a significant impact on the health system worldwide. The organ and tissue donation and transplantation (OTDT) system is no exception and has had to face ethical challenges related to the pandemic, such as risks of infection and resource allocation. In this setting, many Canadian transplant programs halted their activities during the first wave of the pandemic.MethodTo inform future ethical guidelines related to the COVID-19 pandemic or other public health emergencies of international concern, we conducted a (...) literature review to summarize the ethical issues.ResultsThis literature review identified three categories of ethical challenges. The first one describes the general ethical issues and challenges reported by OTDT organizations and transplantation programs, such as risks of COVID-19 transmission and infection to transplant recipients and healthcare professionals during the transplant process, risk of patient waitlist mortality or further resource strain where transplant procedures have been delayed or halted, and resource allocation. The second category describes ethical challenges related to informed consent in the context of uncertainty and virtual consent. Finally, the third category describes ethical issues related to organ allocation, such as social considerations in selecting transplant candidates.ConclusionThis literature review highlights the salient ethical issues related to OTDT during the current COVID-19 pandemic. As medical and scientific knowledge about COVID-19 increases, the uncertainties related to this disease will decrease and the associated ethical issues will continue to evolve. (shrink)

David Murray; VII—Disembodied Brains, Proceedings of the Aristotelian Society, Volume 70, Issue 1, 1 June 1970, Pages 121–138, https://doi.org/10.1093/aristotel.

David Murray; VII—Disembodied Brains, Proceedings of the Aristotelian Society, Volume 70, Issue 1, 1 June 1970, Pages 121–138, https://doi.org/10.1093/aristotel.

This critical note responds to Guiaşu and Tindale’s “Logical fallacies and invasion biology,” from our perspective as ecologists and philosophers of science engaged in debates about invasion biology and invasive species. We agree that “the level of charges and dismissals” surrounding these debates might be “unhealthy” and that “it will be very difficult for dialogues to move forward unless genuine attempts are made to understand the positions being held and to clarify the terms involved.” Although they raise several important scientific, (...) conceptual, and ethical issues at the foundations of invasion biology, we believe Guiaşu and Tindale’s attempts to clarify the debate were unsuccessful. Like some other critics of the field, they tend to misrepresent invasion biology by cherry-picking and constructing “straw people,” inaccurately portraying invasion biology, and thus failing to elevate the dialogue. In this critique, we clarify areas in the invasion biology literature misrepresented by Guiaşu and Tindale. We attempt to provide a more balanced view of areas of reasonable debate within invasion biology, including disputes about empirical evidence, diverse risk attitudes, and other diverse ethical commitments. (shrink)

What are the ethical concerns among the growing populations of business people in Central & Eastern Europe, and how might they be dealt with practically in the course of business life? David Murray has been a management consultant since 1979 working primarily with the Hay Group in the area of strategic organisational change. Since founding Maine Consulting Services in 1991 he spends most of his time in the field of business and professional ethics, also holding a Visiting Fellowship (...) at the University of Central Lancashire. He is chairman of the Professional & Technical Board at the (British) Institute of Quality Assurance and a coordinating editor of the quarterly Organisations & People. Marek Kucia is a social researcher operating his own research agency (which organised the Polish part of this exercise) and an academic teaching sociology, and conducting and co‐ordinating Central European Studies at the Jagiellonian University, Krakow. He studied political science, sociology and philosophy at Krakow and studied for his PhD at Oxford. He has also worked for Gallup, London, in opinion and market research. This survey report is based on presentations made in April 1994 to the EBEN Research Centres Conference in Prague, and in June 1994 to the conference on “Ethics in Transition” organised in Gödöllö, Hungary, by the Democracy after Communism Foundation, Budapest. The authors wish to acknowledge the major contribution to this work of Mr Juraj Kusnierik of the Central European Foundation, SEN, Bratislava, who co‐ordinated the survey exercise. The project was sponsored by The Ethics Development Initiative, CARE, London; the Central European Foundation, SEN, Bratislava, Slovakia; SIS Ltd., Bratislava, Slovakia; and Maine Consulting Services, 16 Acrefield, Blackburn, Lancashire, England BB2 7BJ, to which all correspondence connected with this report should be addressed. (shrink)

What are the ethical concerns among the growing populations of business people in Central & Eastern Europe, and how might they be dealt with practically in the course of business life? David Murray has been a management consultant since 1979 working primarily with the Hay Group in the area of strategic organisational change. Since founding Maine Consulting Services in 1991 he spends most of his time in the field of business and professional ethics, also holding a Visiting Fellowship (...) at the University of Central Lancashire. He is chairman of the Professional & Technical Board at the (British) Institute of Quality Assurance and a coordinating editor of the quarterly Organisations & People. Marek Kucia is a social researcher operating his own research agency (which organised the Polish part of this exercise) and an academic teaching sociology, and conducting and co‐ordinating Central European Studies at the Jagiellonian University, Krakow. He studied political science, sociology and philosophy at Krakow and studied for his PhD at Oxford. He has also worked for Gallup, London, in opinion and market research. This survey report is based on presentations made in April 1994 to the EBEN Research Centres Conference in Prague, and in June 1994 to the conference on “Ethics in Transition” organised in Gödöllö, Hungary, by the Democracy after Communism Foundation, Budapest. The authors wish to acknowledge the major contribution to this work of Mr Juraj Kusnierik of the Central European Foundation, SEN, Bratislava, who co‐ordinated the survey exercise. The project was sponsored by The Ethics Development Initiative, CARE, London; the Central European Foundation, SEN, Bratislava, Slovakia; SIS Ltd., Bratislava, Slovakia; and Maine Consulting Services, 16 Acrefield, Blackburn, Lancashire, England BB2 7BJ, to which all correspondence connected with this report should be addressed. (shrink)

Ultradian rhythms are those that cycle many times in a day and are therefore measured in hours, minutes, seconds or even fractions of a second. In yeasts and protists, a temperature‐compensated clock with a period of about an hour (30–90 minutes) provides the time base upon which all central processes are synchronized. A 40‐minute clock in yeast times metabolic, respiratory and transcriptional processes, and controls cell division cycle progression. This system has at its core a redox cycle involving NAD(P)H and (...) dithiol–disulfide interconversions. It provides an archetype for biological time keeping on longer time scales (e.g. the daily cycles driven by circadian clocks) and underpins these rhythms, which cannot be understood in isolation. Ultradian rhythms are the foundation upon which the coherent functioning of the organism depends. BioEssays 29:465–473, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

This chapter examines the engagement between seventeenth-century Quaker scholars, twentieth-century Quaker theologian Rufus Jones, and the twelfth-century allegorical text Ḥayy ibn Yaqẓān. It argues that HIY was purposely excised from the history of Quaker theological engagement due to a fundamental misunderstanding of the text, which resulted in a complete ignoring of the text by subsequent Quaker theologians, including Rufus Jones. HIY provides an invaluable dialogue partner with Quaker mysticism, which can offer exciting new ways of examining core premises of Quaker (...) mystical theology and practice—human/divine interdependence and the concomitant Quaker balance between contemplative and active mysticism and religious practice—and create opportunities for bringing the different generations of Quaker theology by Robert Barclay and Rufus Jones back into fruitful dialogue. (shrink)

Fechner's conception of psychophysics included both “outer psychophysics” the relation between stimulus intensity and the response reflecting sensation strength, and “inner psychophysics” the relation between neurelectric responses and sensation strength. In his own time outer psychophysics focussed on the form of the psychophysical law, with Fechner espousing a logarithmic law, Delboeuf a variant of the logarithmic law incorporating a resting level of neural activity, and Plateau a power law. One of the issues on which the dispute was focussed concerned the (...) appearance of contrasts if the overall illumination was increased or decreased; another issue was the question of whether a sensation of a “just noticeable difference” established for one value of a sensory dimension appeared the same for a value elsewhere on the dimension. The development of “inner psychophysics” led through the works of Delboeuf, Solomons, Jastrow, and Thurstone to modern signal detection theory. A third line of research, devoted to the question of what was meant by the “measurement” of sensation strength, stemmed from the criticism of Fechner's work by von Kries (1882) and others. Although a valid body of science could be built up without the intervening variable called “sensation strength,” such a science might be a cumbersome representation of reality. When an optical contrast is set up, and its overall illumination is increased or decreased, subjective contrasts involving medium levels of lightness vary little as illumination varies (as a power law based on sensation ratios or a logarithmic law based on sensation differences predict), but subjective contrasts involving extreme levels of lightness might be subject to the effects of other variables. (shrink)

The adoption of the term grievance-fuelled violence reflects the fact that similarities exist between those committing violent acts in the context of grievance in different settings, so potentially allowing the application of insights gained in the study of one group to be applied to others. Given the low base rate of violence against public figures, studies in the field of violence against those in the public eye have tended to use, as a proxy for violence, attempts by the individuals concerned (...) to achieve unwarranted and unwanted proximity to the subject of their attention, given that approach is a necessary prerequisite for most forms of attack. In such studies, one factor that has frequently been considered is whether the making of threats is associated with a subsequent approach. The results have been varied, with no correlation found in some, a negative correlation in others, and a positive correlation in at least one. Such studies have been retrospective, using case files prepared for other purposes, and samples of cases have been selected according to their victims’ sector of employment – for instance, politicians, celebrities, judiciary, and the corporate world. This study of a sample of 126 threat assessment cases, using a prospective methodology, looks at the associations between the making of threats and subsequent approach from a different angle – that of a standardised and validated classification of underlying motivation. It finds that particular types and forms of threat are significantly associated with subsequent approach in cases that are fuelled by grievance, but not in those with the motivation of seeking a relationship. Furthermore, when a sample with a mixture of motivational categories was examined in the manner of previous studies, such associations with threat were not apparent. These results refine the existing understanding of the significance of threats in public-facing cases. Future research projects in this area might usefully incorporate the consideration of underlying motivation, in particular grievance. (shrink)

David Murray; VII—Disembodied Brains, Proceedings of the Aristotelian Society, Volume 70, Issue 1, 1 June 1970, Pages 121–138, https://doi.org/10.1093/aristotel.

It is argued, on the basis of ideas derived from Wittgenstein's Tractatus and Husserl's Logical Investigations, that the formal comprehends more than the logical. More specifically: that there exist certain formal-ontological constants (part, whole, overlapping, etc.) which do not fall within the province of logic. A two-dimensional directly depicting language is developed for the representation of the constants of formal ontology, and means are provided for the extension of this language to enable the representation of certain materially necessary relations. The (...) paper concludes with a discussion of the relationship between formal logic, formal ontology, and mathematics. (shrink)

Generative artificial intelligence (AI) has the potential to transform many aspects of scholarly publishing. Authors, peer reviewers, and editors might use AI in a variety of ways, and those uses might augment their existing work or might instead be intended to replace it. We are editors of bioethics and humanities journals who have been contemplating the implications of this ongoing transformation. We believe that generative AI may pose a threat to the goals that animate our work but could also be (...) valuable for achieving those goals. In the interests of fostering a wider conversation about how generative AI may be used, we have developed a preliminary set of recommendations for its use in scholarly publishing. We hope that the recommendations and rationales set out here will help the scholarly community navigate toward a deeper understanding of the strengths, limits, and challenges of AI for responsible scholarly work. (shrink)

According to a “presence/absence hypothesis,” the hippocampus is not necessary for the formation of learned associations between currently present stimuli and responses (as in classical conditioning), but is necessary whenever a stimulus, if it is to activate a particular response, must first activate a memory-representation of something not present in the here-and-now. The distinction between responses made to present stimuli as opposed to (memories of) absent stimuli was first stressed by Romanes (1889), but we find evidence in the target article (...) that supports the relevance of this distinction to our understanding of hippocampal functioning. (shrink)

Modern literary theory has opened up a variety of new approaches to reading texts of all kinds, however these have been applied mainly to works of prose fiction. This volume contains a collection of essays which attempts to apply these theoretical techniques to works of poetry.

Partial matching theory, which maintains that some memory representations of target items in immediate memory are overwritten by others, can predict both a “theoretical” and an “actual” maximum memory span provided no chunking takes place during presentation. The latter is around 4 ± 2 items, the exact number being determined by the degree of similarity between the memory representations of two immediately successive target items.

Using a particular formula for quantifying the effortlessness that Perruchet & Vinter suggest accompanies the detection of repetition among a set of representations concurrently in consciousness, it is shown that both the Sternberg function and the Cavanagh function, associated with immediate probed recognition tasks and memory span tasks, can be predicted.

Grodzinsky has argued that the traces deleted in Broca's aphasia are “phonetically silent but syntactically active” (sect. 2.). If we assume such traces to be visuospatial in nature, and adopt the term “overwriting” from the author's partial matching theory (1998), we can account for the errors made by Broca's aphasics in comprehending Grodzinsky's Examples (5a), (5b), and (6).

Generative artificial intelligence (AI) has the potential to transform many aspects of scholarly publishing. Authors, peer reviewers, and editors might use AI in a variety of ways, and those uses might augment their existing work or might instead be intended to replace it. We are editors of bioethics and humanities journals who have been contemplating the implications of this ongoing transformation. We believe that generative AI may pose a threat to the goals that animate our work but could also be (...) valuable for achieving those goals. In the interests of fostering a wider conversation about how generative AI may be used, we have developed a preliminary set of recommendations for its use in scholarly publishing. We hope that the recommendations and rationales set out here will help the scholarly community navigate toward a deeper understanding of the strengths, limits, and challenges of AI for responsible scholarly work. (shrink)

Honest signalling theory suggests that humans and chimpanzees can extract socially relevant information relating to personality from the faces of their conspecifics. Humans are also able to extract information from chimpanzees’ faces. Here, we examine whether personality characteristics of chimpanzees, including measures of psychopathy, can be discerned based purely on facial morphology in photographs. Twenty-one chimpanzees were given naïve and expert personality ratings on the Ten Item Personality Inventory (TIPI) and the Chimpanzee Triarchic Model of Psychopathy (CHMP-Tri) before and following (...) behavioural observations. Characteristics relating to openness, conscientiousness, extraversion, and disinhibition could be distinguished from the faces of chimpanzees. Individuals higher on disinhibition have lower scores on conscientiousness and emotional stability and higher scores on extraversion, while those higher on meanness have lower conscientiousness and agreeableness. Facial expressions are linked to personality traits present in the TIPI and CHMP-Tri models: the Relaxed Face and the Grooming Face were displayed more by chimpanzees higher on agreeableness, whereas the Compressed Lips Face was observed more in those individuals higher on boldness, and the Full Open Grin was displayed more by chimpanzees higher on extraversion but lower on emotional stability and conscientiousness. Facial expressions were also found to be associated with particular behavioural contexts, namely the Grooming Face in affiliative contexts and the Relaxed and Relaxed Open Mouth Faces in neutral contexts. Dominant chimpanzees display higher levels of boldness and more Compressed Lips Faces, Relaxed Open Mouth Faces, and Grooming Faces than subordinate individuals. These findings support and extend evidence for an honest signalling system and a personality structure shared between humans and chimpanzees. Future research could further explore how personality is conveyed through the face, perhaps through more than just singular aspects of character, and maybe reflecting what chimpanzees themselves are able to do. (shrink)

‘Force and Understanding’ is the title, or part of the title, of the third section of Hegel's Phänomenologie des Geistes, his ‘phenomenology of spirit’. That was his first book; it was published in 1807 as Volume One of his System of Science. A second volume, he announced, would contain ‘the system of Logic as speculative philosophy, and of the other two parts of philosophy, the sciences of Nature and Spirit’. But no such volume appeared: although in 1812 his Science of (...) Logic was published as ‘the first sequel to the Phenomenology of Spirit in an expanded arrangement of the system’, Hegel added to the 1831 edition a note explaining that since then he had brought out his Encyclopaedia of the Philosophical Sciences ‘in place of the projected second part’. (shrink)

‘Force and Understanding’ is the title, or part of the title, of the third section of Hegel's Phänomenologie des Geistes, his ‘phenomenology of spirit’. That was his first book; it was published in 1807 as Volume One of his System of Science. A second volume, he announced, would contain ‘the system of Logic as speculative philosophy, and of the other two parts of philosophy, the sciences of Nature and Spirit’. But no such volume appeared: although in 1812 his Science of (...) Logic was published as ‘the first sequel to the Phenomenology of Spirit in an expanded arrangement of the system’, Hegel added to the 1831 edition a note explaining that since then he had brought out his Encyclopaedia of the Philosophical Sciences ‘in place of the projected second part’. (shrink)